Partner in Drug Discovery and Development
May 2010 Featured Member:
ADESIS, INC.
WILMINGTON, DE, May 3, 2010 - World Trade Center Delaware is pleased to announce that Adesis, Inc. has been chosen as the featured member for the month of May, 2010.
Who:
Adesis, Inc.
Where:
New Castle, DE
What:
As new concepts for drug discovery are introduced, synthetic organic chemistry remains pivotal to the success of these pharmaceutical programs. Adesis, Inc. is a contract research organization (CRO) specializing in organic synthesis on a scale of mg to multi-kgs.
Outsourcing should be a strategic component of any sponsor's research and development portfolio, instead of an ad hoc decision. It is a decision that factors in 1) cost-risk benefits (internal vs. external), 2) timing, 3) potential CRO's skill set capabilities and business practices. In medicinal chemistry this strategy allows in-house chemists to focus on the design and assembly of new lead molecules vs. routine syntheses that can be outsourced. Virtual biopharmaceutical companies have embraced outsourcing in order to direct maximum start-up funds to reach 'proof-of-concept' instead of creating additional infra-structure.
Services:
Adesis synthesizes compounds and develops new processes for drug manufacturing, producing milligrams to kilogram quantities of new molecules. The services include:
- Early stage proof-of-concept (POC) projects to validate biological hypotheses.
- Validation of screening hits for exploratory medicinal chemistry (hit-to-lead).
- In-depth structure-activity relationship (SAR) studies.
- Intermediates for expediting med chemistry SAR campaigns.
- Drug candidates for in vivo studies.
- Reference agents for bio-profiling.
- Reference metabolites.
- Building blocks for combinatorial chemistry.
- Key intermediates for pharmaceuticals.
- Key intermediates for biomaterial and biosensor applications.
Distinctiveness:
In addition to providing contract chemistry services, Adesis maintains a stock of > 1,000 novel heterocyclic compounds that serve as advanced intermediates for drugs. Clients find it valuable to come to Adesis, knowing they can have a key compound delivered to them in a couple days, or even overnight.
Trivia
About how long does it take the FDA to approve a drug after it has proven to work?
a) 6-12 months
b) 25+ years
c) 10 years
d) after the 1st clinical trial
e) None of the Above
Answer: c
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